Monday, April 28, 2008

Heralding the Dawn of Individualized Genomics

The 2.8 billion contiguous bits of genetic code - the human genome - hold an extraordinary trove of information about human development, physiology, medicine, and evolution.

Already the widely held notion that we have exactly the same genes in the human population is being challenged. The variations revealed in the new genome, dubbed "HuRef," go far beyond previously identified single nucleotide polymorphisms (SNPs), once thought to be the key to differences in human traits and disease susceptibility. New data shows that, in an individual genome, upwards of 44 percent of genes are variable in sequence.

Time's a Wasting!

How does HuRef data influence drug discovery? Will genetic variations allow for tailoring drug efficacy?

Drug discovery and formal FDA processes alone can sometimes take upwards of ten years.

What if your IT infrastructure could be designed to reduce this process time by three years? How many more lives could we save? What is the opportunity cost to a pharmaceutical company’s top-line revenue?

What role does AZ-10GE have to play in reducing the drug discovery timeline by thirty percent? Just ask our customers, or the computer geeks and molecular biologists amongst us.




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